Following the lifting of U.S. sanctions in 2016, U.S. – Burma commercial relations started to grow. Despite targeted sanctions in the wake of the 2021 coup, the United States encourages responsible investment in Burma, and certain bilateral commercial ties still hold some promise. As one of the least developed countries in Asia, Burma has market opportunities in sectors including healthcare, franchising, infrastructure, transportation, professional services, agriculture, and tourism. Specifically, U.S. firms specializing in medical equipment, processed foods, technological services, auto parts, chemicals, computers, textiles, fertilizer, and animal feed could find export potential in Burma. The sectors that currently present possible opportunities for U.S. exporters are agriculture, healthcare, consumer goods, and education. 

Following the coup, some international brands have opted to halt operations, while others paused further expansion.