Taiwan joined the WTO on January 1, 2002. Taiwan became a member of the Asia Pacific Economic Cooperation (APEC) in November 1991 and joined the Central American Bank for Economic Integration in 1992. Taiwan is also a member of the Asian Development Bank (ADB), the Pacific Economic Cooperation Council (PECC), and the Pacific Basin Economic Council (PBEC).

As of August 2022, Taiwan has three free trade agreements (FTA): one with Panama in August 2003, one with Guatemala in July 2005, , and one with El Salvador and Honduras in May 2007. Taiwan terminated a previous FTA with Nicaragua on July 1, 2022, after Nicaragua announced in December 2021 it would unilaterally revoke this bilateral FTA. The FTAs with Panama and El Salvador are still operational, although Panama cut diplomatic ties with Taiwan in June 2017, and El Salvador followed suit in November 2018. In addition, Taiwan inked the Cross-Strait Economic Cooperation Framework Agreement (ECFA) with the PRC in June 2010 and six Economic Cooperation Agreements (ECA): one with New Zealand in July 2013, one with Singapore in November 2013, one with Paraguay in February 2019, one with Eswatini in May 2019, one with the Marshall Islands, and one with Belize in 2020. The ECA with the Marshall Islands was signed in October 2019 and is currently under Legislative Yuan’s review for final approval. Further information about Taiwan’s bilateral and multilateral trade agreements is available on the Board of Foreign Trade’s (BOFT) website.